Canine Disease Information: Cutaneous Mucinosis



  • Type Disease
    Skin
  • Name
    Cutaneous Mucinosis
  • Abbreviation
    CMx
  • Description
    In this condition there is a build-up of abnormal amounts of mucin (thick, clear, sticky fluid) under the skin. It occurs primarily in the Chinese shar pei which has more skin mucin than other breeds to begin with.
  • How Transferred
    unknown. There is probably a relationship between the increased mucin under the skin of the shar pei, and the pronounced skin folds of the breed.
  • What to Look for
    Most often this condition is only cosmetic - that is, it will affect your dog's appearance but not his or her health. Shar peis with mucinosis have excessive skin folding and/or lumps and bumps (vesicles or pockets of mucin). Many dogs seem to outgrow the condition by 5 or so years of age.\nExcessive mucinosis can interfere with breathing if the vesicles are in the back of the mouth. This may cause your dog to snort and snore, and can increase the risks associated with general anesthesia
  • Diagnosis
    Your veterinarian will take a skin biopsy (a simple procedure, done with local anesthetic) for examination by a veterinary pathologist. With this condition, the biopsy will show excessive mucin in the layers of the skin.\nExcessive mucinosis can also occur with hypothyroidism, a condition to which the Chinese shar pei is prone.
  • Treatment
    Dogs with breathing problems are treated with gradually tapering doses of corticosteroids over several weeks, to reduce the amount of mucin. Usually only 1 course of treatment is needed.\nFor the veterinarian: Treatment should be considered in dogs with oropharyngeal involvement, who may experience respiratory arrest under general anesthesia. If repeated treatment is required, hypothyroidism should be ruled out.
  • Veterinarian Information
    The vesicles look similar to those seen in the various autoimmune disorders; however the content (mucin) is thick and sticky rather than serous.\nConcurrent hypothyroidism may lead to severe mucinosis.
  • Breeding Considerations
    It is preferable not to breed affected dogs or close relatives.
  • Known Breeds Affected
    Shar-pei (Chinese shar-pei)

Type Disease

Known Breeds Affected

Type Disease

Known Breeds Affected